RFA: "Mathematical Models of Cytokine/Chemokine Networks in HIV Associated Lung Disease"

Hannah H. Peavy, M.D. and Sandra Colombini Hatch, M.D. Division of Lung Diseases, NHLBI
Joan T. Harmon, M.D., Ph.D., Division of Bioengineering, NIBIB

A new request for applications (RFA) entitled "Mathematical Models of Cytokine/Chemokine Networks in HIV Associated Lung Disease" (RFA-HL-02-009), may be of interest to you and your associates. It was published in the December 7, 2001 "NIH Guide"

The application receipt date is April 12, 2002. It is anticipated that support for this program will begin September 30, 2002. Applicants may request up to five years of support.

The objective of this RFA is to stimulate research on the development and validation of mathematical models of cytokine/chemokine networks involved in the pathogenesis of human immunodeficiency virus type 1 (HIV-1)- associated lung disease. The RFA encourages the use of computational biological methods to create mathematical models of cytokine/chemokine networks (e.g., using nonlinear mathematical techniques) and innovative collaborations between biomathematicians, clinical investigators, and bench scientists. An important aspect of this program will be formation of collaborations to validate the mathematical models using biological experimentation systems. We hope to attract senior and junior level mathematicians and quantitative biologists into this area of biological research. In addition to regular research grants (R01s), the Mentored Quantitative Research Career Development Award (K25) has been included as one of the mechanisms of support under this RFA.