Postdoc position in cancer resistance modeling, Pfizer

We are recruiting a highly motivated postdoctoral candidate to develop and analyze mechanistic mathematical models that incorporate resistance mechanisms across patients and tumors, with the goal of improving predictions of therapeutic response for initial clinical trials. This Postdoctoral Fellowship is an opportunity to work within a dynamic Quantitative Systems Pharmacology group, who are at the forefront of the application of mechanistic systems models to address critical uncertainties in drug discovery and development.

The candidate will work within Pfizer Oncology , which is committed to discovering, investigating, and developing transformative therapies that improve the outlook for cancer patients worldwide. Our strong pipeline includes biologics, small molecules, immunotherapies, and biosimilars, and is centered on exploring a wide array of approaches across many tumor types. We seek to translate the most innovative science into meaningful breakthrough medicines that redefine life with cancer for patients.

In addition, Pfizer’s Postdoctoral Fellows pursue their research and career training in a culture steeped in the translation of basic science discovery into meaningful medicines for patients of all ages and geographies. Postdoctoral trainees are mentored in a setting that places a premium on your preparation for the next stage of your career whether it is a career in industry or academia.

The successful candidate will have earned a Ph.D. in Applied Mathematics, Engineering, Physics, Pharmaceutical Sciences, or other related discipline and has a demonstrated track record in scientific publication. The postdoctoral fellow will develop and analyze mathematical models of cancer resistance that integrate biological knowledge and available data from Pfizer’s preclinical and clinical programs, with the goal of providing tools for pre-clinical to clinical translation, dose selection, and clinical trial design. They will work collaboratively with biologists, clinicians, clinical pharmacologists, pharmacometricians, QSP and nonclinical modelers to improve designs for effective and durable oncology therapies.

For questions about this project or inquiries, please contact Blerta Shtylla (Blerta.Shtylla@pfizer.com ).

To apply follow this link here and more details attached.

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Blerta Shtylla, Ph.D.

Senior Principal Quantitative Systems Pharmacologist

Clinical Pharmacology, Early Clinical Development

Pfizer Worldwide Research, Development, and Medical

La Jolla CA

Blerta.Shtylla@pfizer.com